I love the quality of crisp highlights and bright colours you often get with hand drawn and vector cartoon illustration and animations. This is sometimes referred too as toon shading. You can create this effect in 3D programs such as Blender , but it takes a bit of tweaking to get good results. I use a combination of Blender and Photoshop for my toon look images and animations. You can also download the 3D Blender source file here ( no redistribution or sharing allowed ). This will help you see more clearly how the image is constructed.
I often get asked how I get extra colour, vibrancy and texture into my 3D work.
Often 3D renders can come out a bit flat and boring. The key to vibrancy is comping and mixing lots of renders ( passes ) in a program such a photoshop, that allows you to blend your various renders layers.